High CTG repeat number in nodular thyroid tissue from a myotonic dystrophy patient.
نویسندگان
چکیده
CTG triplet expansion was studied in lymphocytes and thyroid tissue in a patient with myotonic dystrophy (DM) and associated thyroid nodular disease. An approximately 7 fold larger amplification was found in abnormal thyroid tissue compared to lymphocytes, suggesting that anomalies in the putative DM kinase gene might contribute to thyroid dysfunction.
منابع مشابه
Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues.
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 31 11 شماره
صفحات -
تاریخ انتشار 1994